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download ebook pengantar ekonomi mikro sadono sukirno uny download ebook pengantar ekonomi mikro sadono sukirno unyDegradation of cimetidine by Pseudomonas aeruginosa strain S1. An indigenous Pseudomonas aeruginosa strain S1 was isolated from soil and identified as a metabolizing bacteria. The bacterium was able to grow on a wide variety of organic molecules including salicylic acid, cimetidine, cefoxitin, ciprofloxacin, and chloramphenicol. The cimetidine-degrading activity was growth-phase dependent. The bacterial deaminase activity was demonstrated by incubation with the cimetidine-derivatized product in the growth medium. The enzyme was unable to hydrolyze cimetidine in crude extract. Proteinase K-treated and heated bacterial cells retained their degradation activity indicating the participation of a heat-labile enzyme. Cimetidine-degrading activity in strain S1 showed a time-dependent degradation. The degradation was biphasic; the first phase (9-15 h) was found to be irreversible. In the second phase (15-24 h), a significant amount of cimetidine was degraded to the salicylic acid-cimetidine conjugate. These results indicate that the cimetidine-degrading enzyme from strain S1 is a deaminase, which can oxidize the basic amine function of cimetidine, and it is probably a mercapto compound.Frequency, location and severity of arthritic, mammary and uterine implants in untreated women in the UK: a National Case Register study. To estimate the frequency, location and severity of arthritic, mammary and uterine implants in untreated women. Observational study using the British Columbia Cancer Registry (BCCR). Participants recruited via general practice surgeries and clinics and followed up by researchers at 3, 6, 12 and 24 months. A convenience sample of the general population and a cohort of incident cancer cases. Five thousand nine hundred and thirty untreated women aged 30-69 years. Breast, arthritic, mammary and uterine implants at 3, 6, 12 and 24 months. Overall, 750 implants (17 per 1000 women) were found, with 46 per 1000 (6.4 per 1000 breast implants) exhibiting severe or fatal change. U









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Download Ebook Pengantar Ekonomi Mikro Sadono Sukirno Uny __LINK__

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